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Monkeypox Vaccine Page

Florida Department of Health - Hillsborough County

Monkeypox Vaccine (JYNNEOS) BY APPOINTMENT ONLY - (No Walk-ins)

REGISTER HERE for your vaccine appointment.

The Florida Department of Health in Hillsborough County is offering JYNNEOS, by appointment only, to individuals with certain risk factors who are more likely to be exposed to monkeypox.

These groups include:

  • Laboratory personnel and select health care personnel at high risk for monkeypox
  • Close contacts of monkeypox cases
  • Immunocompromised MSM with HIV (< 200 CD4 white blood cells per ml3) with potential exposure
  • Other MSM with a recent history of a sexually transmissible disease
  • All other MSM with HIV who had potential exposure
  • All MSM
  • Other high-risk groups

FDA authorized vaccination by intradermal injection for individuals ages 18+. This will increase the number of doses in each vial to five (5) versus each vial containing a single dose delivered via the traditional subcutaneous (into the muscle) method. At-risk individuals ages <18 can receive the vaccine subcutaneously.

In the context of the current national Public Health Emergency, an alternative regimen may be used for people age ≥18 years under an Emergency Use Authorization beginning August 9, 2022.

Duration of Immunity
Peak immunity is expected to be reached 14 days after the second dose of JYNNEOS vaccine. The duration of immunity after two doses of JYNNEOS is unknown.

We are also offering Hepatitis A, Meningococcal, and COVID-19 vaccines, which you can receive during your scheduled appointment.

Vaccine fact sheets in English and Spanish available for download:

 Appointments are only available online. 

Please be aware, your answers to the exposure assessment questions will be reviewed and your appointment may be canceled, if no high-risk exposure indicated for prophylaxis (vaccine) has been determined.

No walk-ins accepted. If there are no appointments available at this time, please check this website frequently. The Florida Department of Health in Hillsborough County will offer new appointments as additional vaccine becomes available.

For more information on vaccines, click here to be redirected to the CDC.

For more information on monkeypox or if you feel you may have been exposed, see your healthcare provider or call our offices at 813-307-8000.


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